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Topic: Nandrolone joint healing (Read 289 times)
Nandrolone joint healing
January 23, 2021, 06:02:00 PM »
Recent studies in animal models have identified a potential role for nandrolone in joint pain, particularly post rotator cuff tears (31,32). In one such study by Gerber et al. (31), 20 New Zealand white rabbits had their supraspinatus tendon released with musculotendinous retraction and observed over 6 weeks. Rabbits were organized into groups treated with placebo as well as local and systemic administration of nandrolone (31). Nandrolone, given in the phase after tendon release, was found to inhibit fatty infiltration of the supraspinatus muscle and reduced functional impairment of the rotator cuff (31).
An earlier 2010 study by Papaspiliopoulos et al. (32) examined 48 male rabbits that underwent rotator cuff incision and reconstruction after stratification into groups based on local nandrolone administration and immobilization. In this study, local administration of nandrolone proved detrimental to wound healing however, systemic administration was not studied (32). Other limitations include the fact that anabolic steroids affect the tensile strength of tendons that may then cause failure with less elongation (33). Local administration of nandrolone may impair the healing of acute tendon injuries and the perceived benefits to retracted muscle may be outweighed by its effects on tendon healing (34).
Interestingly, Internet and discussion group anecdotal data suggests that nandrolone is effective in decreasing joint pain in bodybuilders. These athletes lift large amounts of weights putting extreme pressure on their joints while reporting improvement and lowered pain with the use of nandrolone. While limited data is available, and dosages are unknown, further investigations are needed to determine the effects of nandrolone on joints in general, and the rotator cuff in particular.
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